Article
Genetic Risk Scores.
Current protocols in human genetics - 11 Oct 2016
Cooke Bailey Jessica N, Igo Robert P
Abstract excerpt
The generation of genome-wide variation data has become commonplace. However, the potential for interpretation and application of these data for clinical assessment of outcomes of interest, and prediction of disease risk, is currently not fully realized. Many common, complex diseases now have numerous, well-established "risk" loci, and likely harbor many genetic determinants with effects too small to be detected...
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