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A Rapid Antibody Enhancement Platform in Saccharomyces cerevisiae Using an Improved, Diversifying CRISPR Base Editor

24 Oct 2023

Abstract excerpt

High Resolution Image Download MS PowerPoint Slide The yeast Saccharomyces cerevisiae is commonly used to interrogate and screen protein variants and to perform directed evolution studies to develop proteins with enhanced features. While several techniques have been described that help enable the use of yeast for directed evolution, there remains a need to increase their speed and ease of use. Here we present...

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PMID: 37873982
DOI: 10.1021/acssynbio.3c00299

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