Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A guide to epigenetics in leukaemia stem cells.

Molecular oncology - 1 Dec 2023

Agrawal-Singh Shuchi, Bagri Jaana, Sakakini Nathalie, Huntly Brian J P

Abstract excerpt

Leukaemia stem cells (LSCs) are the critical seed for the growth of haematological malignancies, driving the clonal expansion that enables disease initiation, relapse and often resistance. Specifically, they display inherent phenotypic and epigenetic plasticity resulting in complex heterogenic diseases. In this review, we discuss the key principles of deregulation of epigenetic processes that shape this disease...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Epigenesis, Genetic
Share to Leukemia, Myeloid, Acute
Share to Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Neoplastic Stem Cells

Share to Stem Cells

Source

Open in PubMed Open full text

Identifiers

PMID: 37872885
DOI: 10.1002/1878-0261.13544
PMCID: PMC10701772

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A guide to epigenetics in leukaemia stem cells.PMID 37872885Read ↗

Single-cell epigenetic and clonal analysis decodes disease progression in pediatric acute myeloid leukemiaSemantic proximity Read ↗

Evolutionary trajectories of myelodysplastic syndromes/neoplasms.Semantic proximity Read ↗

Epigenetic Modifications in Acute Myeloid Leukemia: Prognosis, Treatment, and HeterogeneitySemantic proximity Read ↗

Genetic and epigenetic heterogeneity in acute myeloid leukemia.Semantic proximity Read ↗

Resolving leukemic stem cell heterogeneity and plasticity with single-cell multiomicsSemantic proximity Read ↗

Concise Review: Preleukemic Stem Cells: Molecular Biology and Clinical Implications of the Precursors to Leukemia Stem CellsSemantic proximity Read ↗

Sequential CRISPR gene editing in human iPSCs charts the clonal evolution of myeloid leukemia and identifies early disease targets.Semantic proximity Read ↗

How to drug a leukemic stem cell: deciphering heterogeneity for better specificitySemantic proximity Read ↗

DNMT3A and TET2 in the Pre-Leukemic Phase of Hematopoietic DisordersSemantic proximity Read ↗

Single-cell analysis of acute lymphoblastic and lineage-ambiguous leukemia: approaches and molecular insightsSemantic proximity Read ↗

Chronic Myeloid Leukemia Stem Cell BiologySemantic proximity Read ↗

Single-cell transcriptional mapping reveals genetic and non-genetic determinants of aberrant differentiation in AMLSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.