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Article

Genetic and epigenetic heterogeneity in acute myeloid leukemia.

Current opinion in genetics & development - 1 Feb 2016

Li Sheng, Mason Christopher E, Melnick Ari

Abstract excerpt

Genetic and epigenetic heterogeneity is emerging as a fundamental property of human cancers. Reflecting the genesis of tumors as an evolutionary process driven by clonal selection. The complexity of clonal architecture has been known for many years in the setting of acute myeloid leukemia (AML), based on karyotyping studies. However the true complexity of AMLs is only now being understood thanks to in depth...

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Share to Acute Myeloid Leukemia Research
Share to DNA Methylation
Share to Epigenesis, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27162099
DOI: 10.1016/j.gde.2016.03.011
PMCID: PMC4903929

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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