Article
Evolutionary trajectories of myelodysplastic syndromes/neoplasms.
Seminars in cancer biology - 1 Mar 2026
Creignou Maria, Sarchi Martina, Bernard Elsa, Malcovati Luca
Abstract excerpt
Myelodysplastic syndromes/neoplasms (MDS) are a heterogeneous group of myeloid malignancies characterized by clonality, cytopenia, bone marrow dysplasia, and a variable risk of progression to acute myeloid leukemia (AML). With few therapeutic advances beyond the introduction of hypomethylating agents twenty years ago, MDS remains associated with poor overall survival, limited curative options, and frequent...
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