Article
The parenting hub of the hypothalamus is a focus of imprinted gene action.
PLoS genetics - 1 Oct 2023
Higgs Matthew J, Webberley Anna E, Allan Alasdair J, Talat Moaz, John Rosalind M, Isles Anthony R
Abstract excerpt
Imprinted genes are subject to germline epigenetic modification resulting in parental-specific allelic silencing. Although genomic imprinting is thought to be important for maternal behaviour, this idea is based on serendipitous findings from a small number of imprinted genes. Here, we undertook an unbiased systems biology approach, taking advantage of the recent delineation of specific neuronal populations...
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