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Article

Identification of Cell Type-Specific Effects of DNMT3A Mutations on Relapse in Acute Myeloid Leukemia.

Molecules and cells - 31 Oct 2023

Bae Seo-Gyeong, Kim Hyeoung-Joon, Kim Mi Yeon, Kim Dennis Dong Hwan, Shin So-I, Ahn Jae-Sook, Park Jihwan

Abstract excerpt

Acute myeloid leukemia (AML) is a heterogeneous disease caused by distinctive mutations in individual patients; therefore, each patient may display different cell-type compositions. Although most patients with AML achieve complete remission (CR) through intensive chemotherapy, the likelihood of relapse remains high. Several studies have attempted to characterize the genetic and cellular heterogeneity of AML;...

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Share to DNA Copy Number Variations
Share to DNA (Cytosine-5-)-Methyltransferases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Leukemia, Myeloid, Acute

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Identifiers

PMID: 37853686
DOI: 10.14348/molcells.2023.0093
PMCID: PMC10590706

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