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Article

Predicting susceptibility to inflammaging using a genetic inflammatory index through Prakriti-based phenotypic stratification.

Frontiers in immunology - 1 Jan 2026

Bera Neha, Gowri S Agaje, Syed Nousheen, Govinda Varadhi, Rao A Karteek, Jeeru Jahnavi, Kurthkoti Krishna, Narayanaswamy Kamatham, Jakka Surendar R, Raghawan Akhouri Kishore, Nair Pratibha, Oruganti Baswanth

Abstract excerpt

Inflammaging is chronic low-grade inflammation arising from a progressive imbalance between pro-inflammatory and anti-inflammatory immune networks. The rate of inflammaging exhibits marked interindividual variation owing to differences in the pace of biological aging. Within the two-hit theory of inflammaging, such variability involves both genetic and epigenetic components. Stratification models derived from...

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Identifiers

PMID: 42591277
DOI: 10.3389/fimmu.2026.1854940
PMCID: PMC13461602

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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