Article
Deep molecular tracking over the 12-yr development of endometrial cancer from hyperplasia in a single patient.
Cold Spring Harbor molecular case studies - 1 Dec 2023
Reid Katherine, Camacho-Vanegas Olga, Pandya Deep, Camacho Sandra Catalina, Qiao Rui Fang, Kalir Tamara, Padron-Rhenals Maria M, Beddoe Ann-Marie, Dottino Peter, Martignetti John A
Abstract excerpt
Although the progressive histologic steps leading to endometrial cancer (EndoCA), the most common female reproductive tract malignancy, from endometrial hyperplasia are well-established, the molecular changes accompanying this malignant transformation in a single patient have never been described. We had the unique opportunity to investigate the paired histologic and molecular features associated with the 12-yr...
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