Article
Distinct Genomic Landscapes in Early-Onset and Late-Onset Endometrial Cancer.
JCO precision oncology - 1 Feb 2022
Choi Jungyoon, Holowatyj Andreana N, Du Mengmeng, Chen Zhishan, Wen Wanqing, Schultz Nikolaus, Lipworth Loren, Guo Xingyi
Abstract excerpt
PURPOSE: The spectrum of somatic mutations among women with endometrial cancer (EC) younger than 50 years (early-onset EC) remains unknown. We investigated distinct somatic mutation patterns among early-onset and late-onset (age ≥ 50 years) EC patients. METHODS: This cohort study included individuals age 18+ years diagnosed with pathologically confirmed EC in the American Association of Cancer Research (AACR)...
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