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Article

NOTCH1 and PIK3CA mutation are related to HPV-associated vulvar squamous cell carcinoma.

Pathology, research and practice - 1 Nov 2023

Choschzick M, Stergiou C, Gut A, Zoche M, Ross J S, Moch H

Abstract excerpt

NOTCH1 and PIK3CA are members of important cell signalling pathways that are deregulated in squamous cell carcinomas of various organs. Vulvar squamous cell carcinomas (vulvSCC) are classically divided into two pathways, HPV-associated or HPV-independent, but the effect of NOTCH1 and PIK3CA mutations in both groups is unclear. We analysed two different cohorts of vulvSCC using Hybrid Capture-based Comprehensive...

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Share to Carcinoma, Squamous Cell
Share to Class I Phosphatidylinositol 3-Kinases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 37839360
DOI: 10.1016/j.prp.2023.154877

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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