Article
Genomic characterization of vulvar squamous cell carcinoma.
Gynecologic oncology - 1 Sept 2020
Prieske Katharina, Alawi Malik, Oliveira-Ferrer Leticia, Jaeger Anna, Eylmann Kathrin, Burandt Eike, Schmalfeldt Barbara, Joosse Simon A, Woelber Linn
Abstract excerpt
BACKGROUND: Despite increasing incidence, vulvar squamous cell carcinoma (VSCC) is still a rare disease. Until now, two etiological pathways have been described: a high-risk human papillomavirus (HPV)-dependent route and an HPV-independent pathway often associated with lichen sclerosus. To date, therapeutic strategies in VSCC are not influenced by molecular pathological information and therapeutic options for...
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