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Universal cell donor lines: A review of the current research

12 Oct 2023

Abstract excerpt

Human embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) hold promise for transplantation medicine. Diverse human leukocyte antigen (HLA) profiles necessitate autologous cells or multiple cell lines for therapeutics, incurring time and cost. Advancements in CRISPR-Cas9 and cellular therapies have led to the conceptualization of "off-the-shelf" universal cell donor lines, free of immune...

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PMID: 37832541
DOI: 10.1016/j.stemcr.2023.09.010

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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