Mexican Biobank advances population and medical genomics of diverse ancestries.

doi:10.1038/s41586-023-06560-0

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Article

Mexican Biobank advances population and medical genomics of diverse ancestries.

Nature - 1 Oct 2023

Sohail Mashaal, Palma-Martínez María J, Chong Amanda Y, Quinto-Cortés Consuelo D, Barberena-Jonas Carmina, Medina-Muñoz Santiago G, Ragsdale Aaron, Delgado-Sánchez Guadalupe, Cruz-Hervert Luis Pablo, Ferreyra-Reyes Leticia, Ferreira-Guerrero Elizabeth, Mongua-Rodríguez Norma, Canizales-Quintero Sergio, Jimenez-Kaufmann Andrés, Moreno-Macías Hortensia, Aguilar-Salinas Carlos A, Auckland Kathryn, Cortés Adrián, Acuña-Alonzo Víctor, Gignoux Christopher R, Wojcik Genevieve L, Ioannidis Alexander G, Fernández-Valverde Selene L, Hill Adrian V S, Tusié-Luna María Teresa, Mentzer Alexander J, Novembre John, García-García Lourdes, Moreno-Estrada Andrés

Abstract excerpt

Latin America continues to be severely underrepresented in genomics research, and fine-scale genetic histories and complex trait architectures remain hidden owing to insufficient data1. To fill this gap, the Mexican Biobank project genotyped 6,057 individuals from 898 rural and urban localities across all 32 states in Mexico at a resolution of 1.8 million genome-wide markers with linked complex trait and disease...

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PMID: 37821706
DOI: 10.1038/s41586-023-06560-0
PMCID: PMC10600006

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