Demographic history and biologically relevant genetic variation of Native Mexicans inferred from whole-genome sequencing.

doi:10.1038/s41467-017-01194-z

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Article

Demographic history and biologically relevant genetic variation of Native Mexicans inferred from whole-genome sequencing.

Nature communications - 18 Oct 2017

Romero-Hidalgo Sandra, Ochoa-Leyva Adrián, Garcíarrubio Alejandro, Acuña-Alonzo Victor, Antúnez-Argüelles Erika, Balcazar-Quintero Martha, Barquera-Lozano Rodrigo, Carnevale Alessandra, Cornejo-Granados Fernanda, Fernández-López Juan Carlos, García-Herrera Rodrigo, García-Ortíz Humberto, Granados-Silvestre Ángeles, Granados Julio, Guerrero-Romero Fernando, Hernández-Lemus Enrique, León-Mimila Paola, Macín-Pérez Gastón, Martínez-Hernández Angélica, Menjivar Marta, Morett Enrique, Orozco Lorena, Ortíz-López Guadalupe, Pérez-Villatoro Fernando, Rivera-Morales Javier, Riveros-McKay Fernando, Villalobos-Comparán Marisela, Villamil-Ramírez Hugo, Villarreal-Molina Teresa, Canizales-Quinteros Samuel, Soberón Xavier

Abstract excerpt

Understanding the genetic structure of Native American populations is important to clarify their diversity, demographic history, and to identify genetic factors relevant for biomedical traits. Here, we show a demographic history reconstruction from 12 Native American whole genomes belonging to six distinct ethnic groups representing the three main described genetic clusters of Mexico (Northern, Southern, and...

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PMID: 29044207
DOI: 10.1038/s41467-017-01194-z
PMCID: PMC5647344

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