Article
Analysis of genomic diversity in Mexican Mestizo populations to develop genomic medicine in Mexico.
Proceedings of the National Academy of Sciences of the United States of America - 26 May 2009
Silva-Zolezzi Irma, Hidalgo-Miranda Alfredo, Estrada-Gil Jesus, Fernandez-Lopez Juan Carlos, Uribe-Figueroa Laura, Contreras Alejandra, Balam-Ortiz Eros, del Bosque-Plata Laura, Velazquez-Fernandez David, Lara Cesar, Goya Rodrigo, Hernandez-Lemus Enrique, Davila Carlos, Barrientos Eduardo, March Santiago, Jimenez-Sanchez Gerardo
Abstract excerpt
Mexico is developing the basis for genomic medicine to improve healthcare of its population. The extensive study of genetic diversity and linkage disequilibrium structure of different populations has made it possible to develop tagging and imputation strategies to comprehensively analyze common genetic variation in association studies of complex diseases. We assessed the benefit of a Mexican haplotype map to...
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