Article
Population History and Gene Divergence in Native Mexicans Inferred from 76 Human Exomes.
Molecular biology and evolution - 1 Apr 2020
Ávila-Arcos María C, McManus Kimberly F, Sandoval Karla, Rodríguez-Rodríguez Juan Esteban, Villa-Islas Viridiana, Martin Alicia R, Luisi Pierre, Peñaloza-Espinosa Rosenda I, Eng Celeste, Huntsman Scott, Burchard Esteban G, Gignoux Christopher R, Bustamante Carlos D, Moreno-Estrada Andrés
Abstract excerpt
Native American genetic variation remains underrepresented in most catalogs of human genome sequencing data. Previous genotyping efforts have revealed that Mexico's Indigenous population is highly differentiated and substructured, thus potentially harboring higher proportions of private genetic variants of functional and biomedical relevance. Here we have targeted the coding fraction of the genome and...
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