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Article

Chronic inflammation does not mediate the effect of adiposity on grip strength: results from a multivariable Mendelian randomization study.

Scientific reports - 6 Oct 2023

Norris Tom, Sanderson Eleanor, Cooper Rachel, Garfield Victoria, Pereira Snehal M Pinto

Abstract excerpt

The relationship between adiposity and grip strength (GS) is complex. We investigated whether one pathway through which adiposity affects GS was via chronic inflammation. 367,583 UK Biobank participants had body mass index (BMI), waist-hip-ratio (WHR), C-reactive protein (CRP) and GS data. Univariable Mendelian randomization (MR) and multivariable Mendelian randomization (MVMR) analyses (using inverse variance...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 37803197
DOI: 10.1038/s41598-023-43908-y
PMCID: PMC10558578

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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