Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Conventional and Genetic Evidence on the Association between Adiposity and CKD.

Journal of the American Society of Nephrology : JASN - 1 Jan 2021

Zhu Pengfei, Herrington William G, Haynes Richard, Emberson Jonathan, Landray Martin J, Sudlow Cathie L M, Woodward Mark, Baigent Colin, Lewington Sarah, Staplin Natalie

Abstract excerpt

BACKGROUND: The size of any causal contribution of central and general adiposity to CKD risk and the underlying mechanism of mediation are unknown. METHODS: Data from 281,228 UK Biobank participants were used to estimate the relevance of waist-to-hip ratio and body mass index (BMI) to CKD prevalence. Conventional approaches used logistic regression. Genetic analyses used Mendelian randomization (MR) and data from...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adiposity
Share to Algorithms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Body Mass Index

Share to Mendelian Randomization Analysis

Share to Obesity

Share to Renal Insufficiency, Chronic

Share to United Kingdom

Share to Waist-Hip Ratio

Source

Open in PubMed Open full text

Identifiers

PMID: 33127858
DOI: 10.1681/ASN.2020050679
PMCID: PMC7894659

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Conventional and Genetic Evidence on the Association between Adiposity and CKD.PMID 33127858Read ↗

Contributions of obesity to kidney health and disease: insights from Mendelian randomization and the human kidney transcriptomicsSemantic proximity Read ↗

Obesity as a cause of kidney disease – insights from Mendelian randomisation studiesSemantic proximity Read ↗

Systematic assessment of obesity-related risk factors in renal cancer etiology: A longitudinal risk and Mendelian randomization analysis.Semantic proximity Read ↗

Trans-ethnic Mendelian-randomization study reveals causal relationships between cardiometabolic factors and chronic kidney diseaseSemantic proximity Read ↗

Associations of adiposity, kidney stone disease, and serum calcium concentrations; observational and genetic epidemiological studiesSemantic proximity Read ↗

Causality of visceral adipose tissue on chronic kidney disease and renal function measure indicators, and mediation role of hypertension: Mendelian randomization studySemantic proximity Read ↗

Obesity and Kidney Function: A Two-Sample Mendelian Randomization StudySemantic proximity Read ↗

Trans-ethnic Mendelian randomization study reveals causal relationships between cardio-metabolic factors and chronic kidney diseaseSemantic proximity Read ↗

Causal Effects of Life Course Adiposity on Chronic Kidney Disease: A Mendelian Randomization StudySemantic proximity Read ↗

Age- and Sex-Specific Causal Effects of Adiposity on Cardiovascular Risk FactorsSemantic proximity Read ↗

Effects of general and central adiposity on circulating lipoprotein, lipid, and metabolite levels in UK Biobank: A multivariable Mendelian randomization studySemantic proximity Read ↗

Risk factors mediating the effect of body-mass index and waist-to-hip ratio on cardiovascular outcomes: Mendelian randomization analysisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.