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Revolution of Circulating Tumor DNA: From Bench Innovations to Bedside Implementations

6 Jun 2025

Abstract excerpt

Circulating tumor DNA (ctDNA), a newly developed cancer biomarker, consists of single- or double-stranded DNA fragments that are shed from tumor cells in primary or metastatic sites. They are released into peripheral blood and exhibit distinct characteristics associated with cancer, even in the early stages. With advancements in technology, ctDNA detection has become more diverse and precise, including digital...

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PMID: 40699826
DOI: 10.3390/cimb47060428

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