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Recent Advances From Basic and Clinical Studies of Esophageal Squamous Cell Carcinoma.

Gastroenterology - 1 Dec 2015

Ohashi Shinya, Miyamoto Shin'ichi, Kikuchi Osamu, Goto Tomoyuki, Amanuma Yusuke, Muto Manabu

Abstract excerpt

Esophageal squamous cell carcinoma (ESCC) is one of the most aggressive squamous cell carcinomas and is highly prevalent in Asia. Alcohol and its metabolite, acetaldehyde, are considered definite carcinogens for the esophagus. Polymorphisms in the aldehyde dehydrogenase 2 gene, which encodes an enzyme that eliminates acetaldehyde, have been associated with esophageal carcinogenesis. Studies of the mutagenic and...

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Identifiers

PMID: 26376349
DOI: 10.1053/j.gastro.2015.08.054

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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