Article
Major histocompatibility complex complement (MHC) Bf alleles show trans species evolution between man and chimpanzee.
Scientific reports - 4 Oct 2023
Arnaiz-Villena Antonio, Juarez Ignacio, Sánchez-Orta Alejandro, Martín-Villa José Manuel, Suarez-Trujillo Fabio
Abstract excerpt
HLA and disease studies by using single allele statistics have been fruitless during the last 40 years for explaining association pathogenesis of the associated diseases.Other approaches are necessary to untangle this puzzle. We aim to revisit complement alleleism in humans and primates for both studying MHC and disease association to complotypes and extended MHC haplotypes in order to also explain the positive...
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