Article
Synthetic hyaluronic acid coating preserves the phenotypes of lymphatic endothelial cells.
Biomaterials science - 7 Nov 2023
Saha Sanjoy, Fan Fei, Alderfer Laura, Graham Francine, Hall Eva, Hanjaya-Putra Donny
Abstract excerpt
Lymphatic endothelial cells (LECs) play a critical role in the formation and maintenance of the lymphatic vasculature, which is essential for the immune system, fluid balance, and tissue repair. However, LECs are often difficult to study in vivo and in vitro models that accurately mimic their behaviors and phenotypes are limited. In particular, LECs have been shown to lose their lymphatic markers over time while...
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