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Article

Polymorphisms and haplotypes in the XRCC1 gene and the risk of advanced non-small cell lung cancer.

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer - 1 Dec 2010

Kim In-Suk, Lee Gyeong-Won, Kim Dong Chul, Kim Hoon-Gu, Kim Sunjoo, Oh Sung Yong, Kim Sung-Hyun, Kwon Hyuk-Chan

Abstract excerpt

INTRODUCTION AND HYPOTHESIS: Single-nucleotide polymorphisms (SNPs) and haplotypes in the x-ray repair cross-complementing group 1 (XRCC1) gene, which is one of the base excision repair genes, are thought to be associated with the risk of non-small cell lung cancer (NSCLC). METHODS: We genotyped three coding (Arg280His, Arg399Gln, and Gln632Gln) SNPs and six haplotype-tagging SNPs (htSNPs) for 140 advanced NSCLC...

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Source

Identifiers

PMID: 20978448
DOI: 10.1097/JTO.0b013e3181f46708

Genes

XRCC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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