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Article

Adaptation of HLA testing to characterize the cynomolgus macaque MHC polymorphisms and alloantibody signatures.

HLA - 1 Jan 2024

Agarwal Divyansh, Liu Chengyang, Bhoj Vijay, Kearns Jane, Bharani Tina, Choe Insuk, Vivek Kumar, O'Connor David H, Wiseman Roger W, Duquesnoy René J, Naji Ali, Kamoun Malek

Abstract excerpt

Nonhuman primates are the closest animal models to humans with respect to genetics and physiology. Consequently, a critical component of immunogenetics research relies on drawing inferences from the cynomolgus macaque to inform human trials. Despite the conserved organization of the Major Histocompatibility Complex (MHC) between cynomolgus macaques and humans, MHC genotyping of cynomolgus macaques is challenging...

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PMID: 37784210
DOI: 10.1111/tan.15239

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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