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Article

Vitamin C intake and colorectal cancer survival according to KRAS and BRAF mutation: a prospective study in two US cohorts.

British journal of cancer - 1 Nov 2023

Shi Shanshan, Wang Kai, Ugai Tomotaka, Giannakis Marios, Cazaubiel Jules, Chan Andrew T, Giovannucci Edward L, Nowak Jonathan A, Meyerhardt Jeffrey A, Ogino Shuji, Song Mingyang

Abstract excerpt

BACKGROUND: The associations of vitamin C intake with colorectal cancer (CRC) survival according to tumour KRAS or BRAF mutation status remain unclear. METHODS: We used the inverse probability weighted multivariable Cox proportional hazards regression model to calculate the hazard ratio (HR) of mortality, and spline analysis to evaluate the dose-response relationship in the Nurses' Health Study and Health...

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Identifiers

PMID: 37775523
DOI: 10.1038/s41416-023-02452-2
PMCID: PMC10667518

Genes

BRAF
KRAS
SLC2A1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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