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Article

Dietary intake of one-carbon nutrients and colorectal cancer risk according to TP53 status.

JNCI cancer spectrum - 3 Mar 2026

Nakano Shiori, Yamaji Taiki, Hidaka Akihisa, Shimazu Taichi, Shiraishi Kouya, Kuchiba Aya, Saito Masahiro, Kunishima Fumihito, Nakaza Ryouji, Kohno Takashi, Sawada Norie, Inoue Manami, Tsugane Shoichiro, Iwasaki Motoki

Abstract excerpt

BACKGROUND: Accumulating evidence suggests that one-carbon nutrient intake reduces the risk of colorectal cancer (CRC), although folate fortification has been associated with a temporary increase in CRC incidence. We hypothesized that one-carbon nutrients might harbor preventive and protumor effects on CRC according to tumor conditions and investigated whether the effect of one-carbon nutrients on CRC risk...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41609411
DOI: 10.1093/jncics/pkag009
PMCID: PMC13006204

Genes

TP53

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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