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Exploring the pan-cancer landscape of posttranscriptional regulation

25 Sept 2023

Abstract excerpt

Understanding the mechanisms underlying cancer gene expression is critical for precision oncology. Posttranscriptional regulation is a key determinant of protein abundance and cancer cell behavior. However, to what extent posttranscriptional regulatory mechanisms impact protein levels and cancer progression is an ongoing question. Here, we exploit cancer proteogenomics data to systematically compare mRNA-protein...

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PMID: 37742190
DOI: 10.1016/j.celrep.2023.113172

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