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Article

Mechanosensitive ion channel gene survey suggests potential roles in primary open angle glaucoma.

Scientific reports - 23 Sept 2023

Liu Wendy W, Kinzy Tyler G, Cooke Bailey Jessica N, Xu Zihe, Hysi Pirro, Wiggs Janey L

Abstract excerpt

Although glaucoma is a disease modulated by eye pressure, the mechanisms of pressure sensing in the eye are not well understood. Here, we investigated associations between mechanosensitive ion channel gene variants and primary open-angle glaucoma (POAG). Common (minor allele frequency > 5%) single nucleotide polymorphisms located within the genomic regions of 20 mechanosensitive ion channel genes in the K2P,...

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Identifiers

PMID: 37741866
DOI: 10.1038/s41598-023-43072-3
PMCID: PMC10517927

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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