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Article

Unravelling the complex genetics of common kidney diseases: from variants to mechanisms.

Nature reviews. Nephrology - 1 Nov 2020

Sullivan Katie Marie, Susztak Katalin

Abstract excerpt

Genome-wide association studies (GWAS) have identified hundreds of loci associated with kidney-related traits such as glomerular filtration rate, albuminuria, hypertension, electrolyte and metabolite levels. However, these impressive, large-scale mapping approaches have not always translated into an improved understanding of disease or development of novel therapeutics. GWAS have several important limitations....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32514149
DOI: 10.1038/s41581-020-0298-1
PMCID: PMC8014547

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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