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Article

Modulation of STIM1 by a risk insertion/deletion polymorphism underlying genetics susceptibility to sudden cardiac death originated from coronary artery disease.

Forensic science international - 1 Nov 2021

Zhang Qing, He Yan, Xu Hongfei, Li Lijuan, Guo Yadong, Zhang Jianhua, Cheng Lei, Yu Huan, Dai Yunda, Yang Qi, Yang Zhenzhen, Li Chengtao, Zhang Suhua, Zhu Shaohua, Luo Bin, Gao Yuzhen

Abstract excerpt

Stromal interaction molecule 1 (STIM1), as a dynamic calcium signal transducer and key regulator of cardiomyocyte Ca2+ homeostasis, has been implicated in various pathological processes related to sudden cardiac death originated from coronary artery disease (SCD-CAD). In this study, we performed a systematic variant screening on promoter region of STIM1 to filter potential functional genetic variations. Based on...

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PMID: 34592581
DOI: 10.1016/j.forsciint.2021.111010

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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