Article
Association of APOE ε4 genotype and lifestyle with cognitive function among Chinese adults aged 80 years and older: A cross-sectional study.
PLoS medicine - 1 Jun 2021
Jin Xurui, He Wanying, Zhang Yan, Gong Enying, Niu Zhangming, Ji John, Li Yaxi, Zeng Yi, Yan Lijing L
Abstract excerpt
BACKGROUND: Apolipoprotein E (APOE) ε4 is the single most important genetic risk factor for cognitive impairment and Alzheimer disease (AD), while lifestyle factors such as smoking, drinking, diet, and physical activity also have impact on cognition. The goal of the study is to investigate whether the association between lifestyle and cognition varies by APOE genotype among the oldest old. METHODS AND FINDINGS:...
Topics
- Age Factors
- Aged, 80 and over
- Alcohol Drinking
- Apolipoprotein E4
- Apolipoproteins E
- Body Weight
- China
- Cognition
- Cognitive Aging
- Cognitive Dysfunction
- Cross-Sectional Studies