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Article

Homozygosity for the APOE E4 allele is solely associated with lower cognitive performance in Brazilian community-dwelling older adults: the Bambuí Study.

Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999) - 1 Dec 2012

Quintino-Santos Sandra Regina, Lima-Costa Maria Fernanda, Uchoa Elizabeth, Firmo Josélia Oliveira de Araujo, Moriguchi Emílio Hideyuki, Castro-Costa Erico de

Abstract excerpt

OBJECTIVE: To investigate if APOE E4 allelic status is associated with the cognitive functioning of elderly individuals. METHODS: Participants (n = 1,408) from the Bambuí Cohort Study of Aging were selected based on the results from both variables (APOE genotype and MMSE score). Gender, age, education, marital status, skin color, GHQ score and biological measures were used as confounding factors for adjusting the...

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Identifiers

PMID: 23429815
DOI: 10.1016/j.rbp.2012.06.005

Genes

APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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