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Article

Repression of the major immediate early promoter of human cytomegalovirus allows transcription from an alternate promoter.

The Journal of general virology - 1 Sept 2023

Mason Rebecca, Bradley Eleanor, Wills Mark, Sinclair John, Reeves Matthew

Abstract excerpt

Following infection, the human cytomegalovirus (HCMV) genome becomes rapidly associated with host histones which can contribute to the regulation of viral gene expression. This can be seen clearly during HCMV latency where silencing of the major immediate early promoter (MIEP), normally responsible for expression of the key lytic proteins IE72 and IE86, is mediated by histone methylation and recruitment of...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 37702591
DOI: 10.1099/jgv.0.001894

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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