Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Dynamic histone H3 acetylation and methylation at human cytomegalovirus promoters during replication in fibroblasts.

Journal of virology - 1 Oct 2008

Cuevas-Bennett Christian, Shenk Thomas

Abstract excerpt

Human cytomegalovirus DNA is packaged in virions without histones but associates with histones upon reaching the nucleus of an infected cell. Since transcription is modulated by the interplay of histone modifications, we used chromatin immunoprecipitation to detect acetylation and methylation of histone H3 at viral promoters at different times during the viral replication cycle. Histone H3 at immediate-early...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromatin
Share to Cytomegalovirus
Share to DNA Replication

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA, Viral

Share to Fibroblasts

Share to Histones

Share to Methylation

Share to Protein Processing, Post-Translational

Source

Open in PubMed Open full text

Identifiers

PMID: 18653451
DOI: 10.1128/JVI.00946-08
PMCID: PMC2546956

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Dynamic histone H3 acetylation and methylation at human cytomegalovirus promoters during replication in fibroblasts.PMID 18653451Read ↗

Human cytomegalovirus immediate-early 1 protein facilitates viral replication by antagonizing histone deacetylation.Semantic proximity Read ↗

Lytic infection of permissive cells with human cytomegalovirus is regulated by an intrinsic ‘pre-immediate-early’ repression of viral gene expression mediated by histone post-translational modificationSemantic proximity Read ↗

Chromatin control of human cytomegalovirus infectionSemantic proximity Read ↗

Repression of the major immediate early promoter of human cytomegalovirus allows transcription from an alternate promoter.Semantic proximity Read ↗

Autorepression of the Human Cytomegalovirus Major Immediate-Early Promoter/Enhancer at Late Times of Infection Is Mediated by the Recruitment of Chromatin Remodeling Enzymes by IE86Semantic proximity Read ↗

Temporal Dynamics of Cytomegalovirus Chromatin Assembly in Productively Infected Human CellsSemantic proximity Read ↗

Control of cytomegalovirus lytic gene expression by histone acetylationSemantic proximity Read ↗

Human Cytomegalovirus Infection Elicits Global Changes in Host Transcription by RNA Polymerases I, II, and IIISemantic proximity Read ↗

Canonical and Variant Forms of Histone H3 Are Deposited onto the Human Cytomegalovirus Genome during Lytic and Latent InfectionsSemantic proximity Read ↗

Control of Immediate Early Gene Expression for Human Cytomegalovirus ReactivationSemantic proximity Read ↗

Regulation of Human Cytomegalovirus Transcription in Latency: Beyond the Major Immediate-Early PromoterSemantic proximity Read ↗

Control of human cytomegalovirus gene expression by differential histone modifications during lytic and latent infection of a monocytic cell lineSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.