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From Hazard Rate to Age-at-Onset Distribution: Mind the Gap.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Nov 2023

Chatterjee Nilanjan, Dun Yuzheng

Abstract excerpt

A recent study published in the journal claimed that genetic susceptibility to breast cancer occurs mainly due to rare inherited variants. The claim relies on a set of deductive arguments following observations on patterns of age-at-onset distribution of the disease among twin pairs. In this brief commentary, we point out a major gap in the given argument due to the interchangeable use of hazard rates and...

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PMID: 37698541
DOI: 10.1158/1055-9965.EPI-23-0897

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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