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Frailty, Mental Disorders, and Metabolic Syndrome: A Genetic Association and Mediation Mendelian Randomization Study

2024-01-17

Abstract excerpt

<h4>Objective</h4> To examine the genetic associations of metabolic syndrome (MetS) with frailty and mental disorders [depression, schizophrenia (SCZ), and bipolar disorder (BIP)], along with causality between frailty and MetS and the mediating role of mental disorders. <h4>Methods</h4> The summary-level datasets were obtained from recent genome-wide association studies. The genetic correlation was explored from t...

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Literature Corpus work
9b75bb37-fad6-5306-ae13-af6910359cc3
DOI
10.1101/2024.01.16.24301316
Open publication

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Frailty, Mental Disorders, and Metabolic Syndrome: A Genetic Association and Mediation Mendelian Randomization StudyDOI 10.1101/2024.01.16.24301316
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