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Genomic Analysis in the Categorization of Poorly Differentiated Primary Liver Carcinomas

4 Sept 2023

Abstract excerpt

A subset of primary liver carcinomas (PLCs) cannot be classified as hepatocellular carcinoma (HCC) or intrahepatic cholangiocarcinoma (iCCA) based on morphology and immunohistochemistry (IHC). This includes tumors with morphology suggestive of HCC but lacking hepatocellular marker expression, tumors with ambiguous morphology characterized by co-expression of hepatocellular and cholangiocytic markers, and...

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PMID: 37661782
DOI: 10.1097/pas.0000000000002116

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