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Article

Genomic characterization of rare molecular subclasses of hepatocellular carcinoma.

Communications biology - 4 Oct 2021

Damrauer Jeffrey S, Smith Markia A, Walter Vonn, Thennavan Aatish, Mose Lisle E, Selitsky Sara R, Hoadley Katherine A

Abstract excerpt

Primary liver cancer, consisting of both cholangiocarcinoma (CCA) and hepatocellular carcinoma (HCC), is the second leading cause of cancer deaths worldwide. Our goal is to genomically characterize rare HCC subclasses to provide insight into disease biology. Leveraging The Cancer Genome Atlas (TCGA) to perform a combined analysis of CCA (n = 36) and HCC (n = 275), we integrated multiple genomic platforms, to...

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Topics

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Share to Carcinoma, Hepatocellular
Share to DNA Copy Number Variations

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 34608257
DOI: 10.1038/s42003-021-02674-1
PMCID: PMC8490450

Genes

BAP1
IDH1
KRT19
SOX9
TP53

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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