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Article

Molecular features of primary hepatic undifferentiated carcinoma.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 May 2022

Tsai Jia-Huei, Jeng Yung-Ming, Lee Chia-Hsiang, Liau Jau-Yu

Abstract excerpt

The clinicopathological and molecular characteristics of primary hepatic undifferentiated carcinoma are poorly defined. It is speculated that primary hepatic undifferentiated carcinoma develops in the setting of preceding primary hepatic carcinoma. We investigated 14 primary hepatic undifferentiated carcinomas through targeted next-generation sequencing and immunohistochemistry. A panel of genes commonly mutated...

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PMID: 34949765
DOI: 10.1038/s41379-021-00970-z

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