Article
Solid-Basaloid Adenoid Cystic Carcinoma of the Breast: An Aggressive Subtype Enriched for Notch Pathway and Chromatin Modifier Mutations With MYB Overexpression.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Dec 2023
Shamir Eliah R, Bean Gregory R, Schwartz Christopher J, Vohra Poonam, Wang Aihui, Allard Grace M, Wolsky Rebecca J, Garcia Joaquin J, Chen Yunn-Yi, Krings Gregor
Abstract excerpt
Adenoid cystic carcinoma (AdCC) is a rare triple-negative breast cancer analogous to its extramammary counterparts. Diagnosis of the more aggressive solid-basaloid variant of AdCC (SB-AdCC) can be challenging due to poorly defined histopathologic and molecular features. We characterized 22 invasive and in situ basaloid carcinomas by morphology, immunohistochemistry, genetics, and MYB status using multiple...
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