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Article

Multifunctions of CRIF1 in cancers and mitochondrial dysfunction

3 Oct 2022

Abstract excerpt

Sustaining proliferative signaling and enabling replicative immortality are two important hallmarks of cancer. The complex of cyclin-dependent kinase (CDK) and its cyclin plays a decisive role in the transformation of the cell cycle and is also critical in the initiation and progression of cancer. CRIF1, a multifunctional factor, plays a pivotal role in a series of cell biological progresses such as cell cycle,...

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PMID: 36263222
DOI: 10.3389/fonc.2022.1009948

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