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Coming of Age: Targeting Cyclin K in Cancers

11 Aug 2023

Abstract excerpt

Cyclins and cyclin-dependent kinases (CDKs) play versatile roles in promoting the hallmarks of cancer. Therefore, cyclins and CDKs have been widely studied and targeted in cancer treatment, with four CDK4/6 inhibitors being approved by the FDA and many other inhibitors being examined in clinical trials. The specific purpose of this review is to delineate the role and therapeutic potential of Cyclin K in cancers....

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PMID: 37626854
DOI: 10.3390/cells12162044

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