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Cyclin-dependent kinases

30 Jun 2014

Abstract excerpt

Cyclin-dependent kinases (CDKs) are protein kinases characterized by needing a separate subunit - a cyclin - that provides domains essential for enzymatic activity. CDKs play important roles in the control of cell division and modulate transcription in response to several extra- and intracellular cues. The evolutionary expansion of the CDK family in mammals led to the division of CDKs into three...

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PMID: 25180339
DOI: 10.1186/gb4184

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