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Article

Somatic mutation effects diffused over microRNA dysregulation.

Bioinformatics (Oxford, England) - 2 Sept 2023

Yu Hui, Jiang Limin, Li Chung-I, Ness Scott, Piccirillo Sara G M, Guo Yan

Abstract excerpt

MOTIVATION: As an important player in transcriptome regulation, microRNAs may effectively diffuse somatic mutation impacts to broad cellular processes and ultimately manifest disease and dictate prognosis. Previous studies that tried to correlate mutation with gene expression dysregulation neglected to adjust for the disparate multitudes of false positives associated with unequal sample sizes and uneven class...

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Identifiers

PMID: 37624931
DOI: 10.1093/bioinformatics/btad520
PMCID: PMC10474951

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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