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Article

Pan-cancer analysis of somatic mutations in miRNA genes.

EBioMedicine - 1 Nov 2020

Urbanek-Trzeciak Martyna O, Galka-Marciniak Paulina, Nawrocka Paulina M, Kowal Ewelina, Szwec Sylwia, Giefing Maciej, Kozlowski Piotr

Abstract excerpt

BACKGROUND: miRNAs are considered important players in oncogenesis, serving either as oncomiRs or suppressormiRs. Although the accumulation of somatic alterations is an intrinsic aspect of cancer development and many important cancer-driving mutations have been identified in protein-coding genes, the area of functional somatic mutations in miRNA genes is heavily understudied. METHODS: Here, based on the analysis...

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Identifiers

PMID: 33038763
DOI: 10.1016/j.ebiom.2020.103051
PMCID: PMC7648123

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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