Article
Evaluation of population structure inferred by principal component analysis or the admixture model.
Genetics - 4 Oct 2023
van Waaij Jan, Li Song, Garcia-Erill Genís, Albrechtsen Anders, Wiuf Carsten
Abstract excerpt
Principal component analysis (PCA) is commonly used in genetics to infer and visualize population structure and admixture between populations. PCA is often interpreted in a way similar to inferred admixture proportions, where it is assumed that individuals belong to one of several possible populations or are admixed between these populations. We propose a new method to assess the statistical fit of PCA...
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