Article
Exploring Population Structure with Admixture Models and Principal Component Analysis.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2020
Liu Chi-Chun, Shringarpure Suyash, Lange Kenneth, Novembre John
Abstract excerpt
Population structure is a commonplace feature of genetic variation data, and it has importance in numerous application areas, including evolutionary genetics, conservation genetics, and human genetics. Understanding the structure in a sample is necessary before more sophisticated analyses are undertaken. Here we provide a protocol for running principal component analysis (PCA) and admixture proportion...
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