Article
Inferring Population Structure and Admixture Proportions in Low-Depth NGS Data.
Genetics - 1 Oct 2018
Meisner Jonas, Albrechtsen Anders
Abstract excerpt
We here present two methods for inferring population structure and admixture proportions in low-depth next-generation sequencing (NGS) data. Inference of population structure is essential in both population genetics and association studies, and is often performed using principal component analysis (PCA) or clustering-based approaches. NGS methods provide large amounts of genetic data but are associated with...
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