Article
MBOAT7 in liver and extrahepatic diseases.
Liver international : official journal of the International Association for the Study of the Liver - 1 Nov 2023
Caddeo Andrea, Spagnuolo Rocco, Maurotti Samantha
Abstract excerpt
MBOAT7 is a protein anchored to endomembranes by several transmembrane domains. It has a catalytic dyad involved in remodelling of phosphatidylinositol with polyunsaturated fatty acids. Genetic variants in the MBOAT7 gene have been associated with the entire spectrum of non-alcoholic fatty liver (NAFLD), recently redefined as metabolic dysfunction-associated fatty liver disease (MAFLD) and, lately, steatotic...
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